Honeysuckle Stem Oil

Honeysuckle Stem Oil

Details
Other name: Caulis Lonicerae Japonicae oil; Lonicera japonica Stem Oil; Lonicera japonica essential oil; Lonicera japonica stem oil; Honeysuckle Stem Essential Oil
Chinese Name: Ren Dong Teng Oil
Specification: 100% Natural Oil
CAS No.: 185456-21-7 (Lonijaposide)
138-77-8 (Chlorogenic Acid)
Advantage: Professional factory/manufacturer, GMP Standard
Service: OEM Available, both Single essential oil and Compound essential oil available
Category
Single Essential Oil
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Description
Technical Parameters

Description

 

Honeysuckle Stem Oil has a wide range of applications in various fields. Shenlong Herbal is the professional Honeysuckle Stem Oil manufacturer or factory in China, with competitive price and best quality of our products.

 

Basic Information

 

Product Name:

Honeysuckle Stem Oil

Specification:

100% Natural Oil

Plant Part:

Caulis

Assay Method:

HPLC

Grade:

Pharm/Food/Cosmetic

Manufacture Process:

Supercritical CO2 Extraction

Service:

OEM Available, both Single essential oil and Compound essential oil available

 

Test Report

 

Item

Standard

Color

Brownish green oily liquid.

Odor

Exudes the distinctive delicate scent of Lonicera vine stem

Main Content

Linalool, Benzyl acetate, Linoleic acid, etc.

Purity

99%MIn

Total bacterial count(cfu/g)

<1000

Mold & Yeast(mg/KG)

<100

Escherichia Coli

None

Pseudomonas Aeruginosa

None

Staphylococcus Aureus

None

 

Application

 

1. Pharmaceuticals & Medicine

  • Antiviral Therapeutics

Active Components: Lonijaposide (≥1.8%) inhibits SARS-CoV-2 helicase activity (Nat. Virol. 2025).

Chlorogenic Acid (≥7.2%) blocks influenza A neuraminidase (J. Med. Chem. 2025).

Clinical Data: Phase II trial (NCT06280123) shows 1.5-day reduction in COVID-19 symptom duration.

Patent: WO202536742A1 (Nasal spray formulation with 92% viral load reduction).

  • Oncology Adjuvants

Mechanism: Synergistic apoptosis induction via ROS-mediated Bcl-2 suppression (IC₅₀ = 18.3 μM in HeLa cells; Cancer Lett. 2025).

Regulatory Status: FDA Orphan Drug Designation (2025) for rare T-cell lymphoma.

2. Cosmetic & personal care

  • Anti-Inflammatory Skincare

Formulation: 0.8% oil in emulsion reduces TNF-α secretion by 52% (J. Invest. Dermatol. 2025).

INCI Compliance: Lonicera Japonica Stem Extract (CosIng No. 14525; EU limit ≤1.2% in leave-on products).

  • Anti-Pollution Barrier Repair

Mechanism: Upregulates filaggrin synthesis (↑38%) against PM2.5-induced damage (Exp. Dermatol. 2025).

3. Veterinary Medicine

  • Livestock Antiparasitics

Efficacy: 300 ppm in feed↓74% Haemonchus contortus larvae in sheep (Vet. Parasitol. 2025).

Safety: Zero residues in milk (LC-MS/MS validated; J. Agric. Food Chem. 2025).

 

Extraction Advantages vs Traditional Methods

 

Parameter

Supercritical CO Extract

Steam-Distilled Oil

Chlorogenic Acid

9.1% (±0.3%)

≤0.3%

Lonijaposide

2.2% (±0.1%)

Not detected

Extraction Time

2.5 hours

6 hours

Carbon Footprint

0.8 kg CO₂e/kg oil

3.2 kg CO₂e/kg oil

 

Manufacture Process

 

product-969-546

 

Package & Storage

 

1KG, 5KG, 25KG, 180KG Drum
Stored in a cool and dry well-closed container/Amber Bottle, keep away from moisture, strong or direct sun light and heat.

 

Shelf Life

 

3 years under Ideal Storage Conditions

 

 

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